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Break Through Cancer empowers outstanding researchers and physicians to both intercept and find cures for the deadliest cancers by stimulating Radical Collaboration™.

Break Through Cancer empowers outstanding researchers and physicians to both intercept and find cures for the deadliest cancers by stimulating Radical Collaboration™.

Empowers

Break Through Cancer is committed to reducing the day-to-day barriers to cross-institutional collaboration such as contract negotiations, data sharing, intellectual property, and authorship policies.

Outstanding Researchers and Physicians

Break Through Cancer is a first-of-its-kind collaboration of five of the top cancer research centers in the world: Dana-Farber Cancer Institute, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, MIT’s Koch Institute for Integrative Cancer Research, The University of Texas MD Anderson Cancer Center, and Memorial Sloan Kettering Cancer Center.

deadliestcancers

Break Through Cancer is focused on several of the world’s deadliest cancers. These are diseases with poor prognoses for which progress has been very slow.

RadicalCollaboration™

Radical Collaboration™ is the expectation of all Break Through Cancer researchers, physicians, and other partners. Radical Collaboration™ requires sharing discoveries and data in real time, a trust and willingness to critique each other’s ideas, and a sense of urgency knowing that lives are at stake.

IT’S ALL ABOUT THE PEOPLE

David A. Reardon, MD “Break Through Cancer is a unique opportunity for some of the leading cancer researchers and clinicians to come together and pool their experiences, and to work together to accelerate developments, advances, and ultimately improvement and outcome for our patients” Learn More Dana-Farber Cancer Institute Accelerating GBM Therapies Through Serial Biopsies Anirban Maitra, MBBS "Break Through Cancer is a completely novel and innovative way of doing cancer research where instead of doing this as a single institution or a single lab, you bring together institutions across the spectrum with varying expertise, different disciplines, all come together as a single entity focused on the hardest questions in cancer." Learn More The University of Texas MD Anderson Cancer Center Conquering KRAS in Pancreatic Cancer Paola A. Guerrero, PhD “I guess for me, radical collaboration is when you can actually push boundaries and take a risk based on thinking what is the best for, for research” Learn More The University of Texas MD Anderson Cancer Center Conquering KRAS in Pancreatic Cancer Laura D. Wood, MD, PhD Learn More "The TeamLab is really unique and different from anything that I've done in the past. In particular, the multi-institutional and collaborative nature and the broad expertise in the TeamLab. I think it's the diversity of the TeamLab, the breadth of expertise, and having all of those voices together in one room to really try to solve big problems." The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins Leveraging Spatial Technology to Demystify Pancreatic Cancer Therapies in Patients Kara Long, MD, MSc “This endeavor has allowed us to think bigger and in a different way...it gave us the, the voice to use creativity and think big to try to come up with a plan that's gonna actually keep people from getting cancer in our lifetimes” Memorial Sloan Kettering Cancer Center Intercepting Ovarian Cancer Learn More Andrew Lane, MD, PhD “We have clinicians, scientists, clinicians who don't ever see a pipette. We have scientists who don't ever see a patient,and everybody has a seat at the table and everybody's ideas count... So that is a bit radical compared to the way we usually do business” Dana-Farber Cancer Institute Identifying, Understanding and Eradicating Measurable Residual Disease in Patients with Acute Myeloid Leukemia Learn More Kenny Yu, MBBS, PhD, FRCS "It's like an experiment in radical team science. I think it's unusual to have so much talent and expertise put into one place towards a single purpose. And for us, all of us deal with brain cancer all the time, and I think having the singular mission is what defines this team, and it's really been a privilege to be part of." Memorial Sloan Kettering Cancer Center Accelerating GBM Therapies Through Serial Biopsies Learn More Jessica Lin, MD "There’s a ceiling to how much can be achieved, and at what pace, with single isolated institutions. But when multiple centers that are sharing the same goal come together to make progress we can advance the science in a really transformative way." Massachusetts General Hospital PoweRD 2 Cure ALK+ Lung Cancer Learn More Koichi Takahashi, MD, PhD Learn More "There are lots of advantages in interacting with other peoples and other institutions. Number one is that there's a limit of what you can do by one person. And number two, just by talking with someone whose background is different, you get new ideas..it creates ideas and the foundation for the discovery" The University of Texas MD Anderson Cancer Center Targeting Clonal Hematopoiesis to Prevent Acute Myeloid Leukemia

UPDATES AND NEWS

Insights & Updates

2025 Year in Review: Our Scientific Progress and Clinical Impact

Press Release

New Coalition of Leading Cancer Research Organizations Launched to Accelerate Early Detection of Deadly Cancers

Press Release

Five Leading Cancer Centers Unite to Target CD123 and Eradicate Hidden Leukemia Cells

Patient-Story

More Than a Patient: How Holly Folgia Turned Her Cancer Journey Into Impact

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Your contribution fuels groundbreaking research in some of the most challenging cancers. Every gift accelerates progress. For more information please contact Michaela Forand at MF@breakthroughcancer.org or 1-800-757-9881 ext 2.

Break Through Cancer
101 Rogers Street
Suite 3A
Cambridge, MA 02142
Info@breakthroughcancer.org
1-800-757-9881

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