Back to the top

No More “Wait and See”: Two Clinical Trials Target the Origins of Recurrent Ovarian Cancer

News Release For Immediate Release Media Contact: Kari McHugh Kari.McHugh@breakthroughcancer.org   No More “Wait and See”: Two Clinical Trials Target the Origins of Recurrent Ovarian Cancer Break Through Cancer scientists are evaluating a “second-look” technique to measure and destroy persistent cancer cells resistant to frontline chemotherapy. (CAMBRIDGE, MASS.) September 26, 2024 – After initial therapy to treat ovarian cancer, a small number of cancer cells, undetectable on scans, often linger in the body. These cells, referred to as minimal residual disease (MRD), are the seed from which cancer can and does recur for most women diagnosed with stage III or......

Continue reading

Break Through Cancer and ALK Positive, Inc. Team Up to Conquer ALK-Positive Lung Cancer with a $2 Million, Multi-year, Research Partnership

News Release For Immediate Release Media Contact: Kari McHugh Kari.McHugh@breakthroughcancer.org   Break Through Cancer and ALK Positive, Inc. Team Up to Conquer ALK-Positive Lung Cancer with a $2 Million, Multi-year, Research Partnership   CAMBRIDGE, MA, May 9, 2024 /Break Through Cancer announces a new partnership with ALK Positive Inc. (ALK Positive), a foundation funded by patients with ALK-positive lung cancer and their families. ALK Positive and Break Through Cancer are joining forces to fund a new initiative in lung cancer research with the hope of creating durable responses and cures for patients with ALK-positive lung cancer. ALK Positive is the......

Continue reading

Radical Collaboration: Reimagining Cancer Team Science | Nature Discovery

Radical Collaboration: Reimagining Cancer Team Science By: Jesse Boehm and Tyler Jacks Here, we define a future of cancer team science adopting “radical collaboration”—in which six “Hallmarks of Cancer Collaboration” are utilized to propel cancer teams to reach new levels of productivity and impact in the modern era. This commentary establishes a playbook for cancer team science that can be readily adopted by others. Read More at Cancer Discovery...

Continue reading

Reimagining Cancer Team Science: Six Hallmarks of Cancer Collaboration

News Release For Immediate Release Media Contact: Kari McHugh KM@breakthroughcancer.org   Reimagining Cancer Team Science: Six Hallmarks of Cancer Collaboration A new commentary in Cancer Discovery presents a playbook of best practices for cancer team science in the modern era. (CAMBRIDGE, MASS.) April 4, 2024 – The oncology community has a powerful opportunity to speed the creation of impactful new treatments by adopting a modern playbook for collaboration, according to scientists from Break Through Cancer and other team-oriented cancer organizations working together in a commentary in the journal Cancer Discovery Jesse Boehm and Tyler Jacks of Break Through Cancer, a......

Continue reading

Breakthroughs In The Battle Against Cancer With Tyler Jacks | Health Gig Podcast

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 in the Battle Against Cancer with Tyler Jacks This week, explore the world of cutting-edge cancer research with Doro, Tricia, and guest Tyler Jacks, PhD, President of Break Through Cancer. Together, they discuss the organization's patient-centric approach and the proactive ways Break Through Cancer is propelling scientific breakthroughs. Dr. Jacks shares innovative approaches to early-stage cancer prevention and the discoveries Break Through Cancer has made in pancreatic cancer, glioblastoma, ovarian cancer, and more. Throughout the conversation, experience the passion and hope for a cancer-free future. Hear on SoundCloud...

Continue reading

Break Through Cancer Summit Advances ‘Radical Collaboration’ Among Top Cancer Centers

Scientists and funders unite to tackle urgent projects across four deadly cancers at annual meeting. Carol Aghajanian, M.D., and other members of the Targeting Minimal Residual Disease in Ovarian Cancer TeamLab at the 2023 Break Through Cancer Summit (KIAWAH, SOUTH CAROLINA) November 5, 2023 -- Today, Break Through Cancer, a collaborative medical research foundation, welcomes over 120 scientists and physicians from five leading cancer centers, as well as representatives from ARPA-H, to its annual Summit, November 5th to 8th in Kiawah, South Carolina. The gathering arrives at an unprecedented moment for oncology, when breakthroughs in genomic technologies, machine learning, and novel......

Continue reading

Break Through Cancer Launches Two TeamLabs Targeting Acute Myelogenous Leukemia (AML)

Break Through Cancer Launches Two TeamLabs Targeting Acute Myelogenous Leukemia (AML) Novel research program embracing radical collaboration to discover potential AML treatments (CAMBRIDGE, MASS.) MAY 16, 2023 – Break Through Cancer, a collaborative medical research organization empowering researchers and physicians from top cancer research institutions to intercept and find cures for several of the world’s deadliest cancers, is announcing the launch of the Targeting Clonal Hematopoiesis to Prevent AML TeamLab and the Eradicating Minimal Residual Disease in AML TeamLab. AML begins in the blood-forming cells of the bone marrow and rapidly moves into the bloodstream, where it can quickly spread......

Continue reading

Break Through Cancer, A New Research Consortium, Names First Class of Scientists Designated as Catalysts for Innovation and Collaboration

Break Through Cancer, A New Research Consortium, Names First Class of Scientists Designated as Catalysts for Innovation and Collaboration Highly skilled professional scientists at partner institutes will spur development of novel approaches to understanding cancer and developing new treatment strategies (CAMBRIDGE, MASS.) APRIL 25, 2023 – Break Through Cancer, a foundation designed to find new solutions to some of the most intractable challenges in cancer, has named four individuals as Break Through Cancer Scientists—Neelkanth Bardhan, Sreyashi Basu, Paola A. Guerrero, and Thomas R. Pisanic II. They are professional scientists who cooperate on and lead projects with the skills, knowledge, and......

Continue reading

Removing fallopian tubes can prevent ovarian cancers without causing menopause. But who’s eligible? | WBUR

JTNDaWZyYW1lJTIwd2lkdGglM0QlMjIxMDAlMjUlMjIlMjBoZWlnaHQlM0QlMjIxMjQlMjIlMjBzY3JvbGxpbmclM0QlMjJubyUyMiUyMGZyYW1lYm9yZGVyJTNEJTIybm8lMjIlMjBzcmMlM0QlMjJodHRwcyUzQSUyRiUyRnBsYXllci53YnVyLm9yZyUyRmhlcmVhbmRub3clMkYyMDIzJTJGMDMlMkYxNiUyRm92YXJpYW4tY2FuY2Vycy1mYWxsb3BpYW4tdHViZXMlMjIlM0UlM0MlMkZpZnJhbWUlM0U=Removing fallopian tubes can prevent ovarian cancers without causing menopause. But who's eligible? The American Cancer Society estimates that more than 19,000 women will be diagnosed with ovarian cancer this year. More than 13,000 of them will die from the disease, which is difficult to diagnose and to treat. That's why the Ovarian Cancer Research Alliance recommended earlier this year that women (particularly those done having children) consider adding surgery to remove their fallopian tubes to pelvic surgeries like hysterectomies or tubal ligations since most ovarian cancers start in the tubes. Among those performing the surgery is Dr. Michael Worley,......

Continue reading

More physicians are calling for fallopian tube removal to prevent ovarian cancer | STAT

More physicians are calling for fallopian tube removal to prevent ovarian cancer By Zeina Mohammed — Boston GlobeFeb. 23, 2023 Ovarian cancer has long been one of the deadliest cancers to strike women. No tests are available to detect it early, so most patients are diagnosed in later stages, when the cancer is more likely to have spread. Fewer than half of women survive 5 years past their diagnosis, and 80 percent have no known risk factors. Now, a growing chorus of physicians is recommending a procedure that can significantly reduce the chances of developing ovarian cancer. The procedure is......

Continue reading