Rather than soliciting proposals and operating a conventional request for proposal model, we build collaborative research programs from the ground up, identifying bold, high-impact scientific challenges and co-designing solutions with leading experts. This is purpose-built radical collaboration, where a shared culture replaces competition with trust and fosters a collective ambition to urgently help patients

TeamLabs bring together clinicians, scientists, engineers, and data experts across institutions and disciplines. TeamLabs are the signature engine of our model: deeply integrated, multi-institutional research teams working in real-time to solve focused cancer challenges. TeamLabs break through silos and accelerate translation from discovery to patient benefit

Our dedicated Scientific Portfolio Managers (“Liaisons”), a key role at Break Through Cancer, go far beyond typical grant managers. They serve as embedded strategists, connectors, and problem-solvers, empowered to remove barriers and drive executional excellence. From aligning priorities to managing inter-institutional agreements, we take on the complexity, so our researchers can focus on science

Our cloud-based Data Science Hub (DASH) enables real-time, multi-institutional data sharing, access, and analysis. DASH serves as the connective tissue that powers TeamLabs, allowing large-scale datasets to be transformed into discovery pipelines. This is data sharing without friction, built upon a foundation of trust, transparency, and shared credit

From industry collaborations to academic contracting, we partner with our collaborators to cut through the red tape that slows science. By harmonizing agreements and accelerating processes, we endeavor to make it easier for researchers to work across institutions and with the private sector, by turning tangled contracts into shared momentum

Break Through Cancer’s staff of 22 professionals serve our funded scientific teams across the entire research lifecycle. This end-to-end model ensures that teams of researchers are supported at every stage of discovery, from initial concept development to clinical impact.