New collaborative effort aims to cure ALK-positive lung cancer December 6, 2024 Lung cancer is the leading cause of cancer death worldwide, with various subtypes affecting millions of people each year. Among these, ALK-positive lung cancer frequently strikes younger people who have never smoked, including those aged between 20 and 50. Upon diagnosis, 80% of individuals already have stage 4 metastatic cancer, spread beyond the lungs to other parts of the body. Despite initially effective ALK inhibitor treatments, the cancer recurs in most patients, and there are about 70,000 people living with ALK+ lung cancer in the United States. Read......

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Break Through Cancer launches the PoweRD 2 Cure ALK+ Lung Cancer TeamLab December 6, 2024 Break Through Cancer has launched the PoweRD 2 Cure ALK+ Lung Cancer TeamLab, a collaboration among nine leading cancer research institutions, including Break Through Cancer’s five partner institutions: Dana-Farber Cancer Institute, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Memorial Sloan Kettering Cancer Center, MIT’s Koch Institute for Integrative Cancer Research, and the University of Texas MD Anderson Cancer Center, as well as newly engaged collaborators from Mass General Brigham, Boston Children’s Hospital, the University of Colorado Cancer Center and Vanderbilt University Medical Center. Read......

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Radical Collaboration: Reimagining Cancer Team Science By: Jesse Boehm and Tyler Jacks Here, we define a future of cancer team science adopting “radical collaboration”—in which six “Hallmarks of Cancer Collaboration” are utilized to propel cancer teams to reach new levels of productivity and impact in the modern era. This commentary establishes a playbook for cancer team science that can be readily adopted by others. Read More at Cancer Discovery...

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JTNDaWZyYW1lJTIwd2lkdGglM0QlMjIxMDAlMjUlMjIlMjBoZWlnaHQlM0QlMjIxMjQlMjIlMjBzY3JvbGxpbmclM0QlMjJubyUyMiUyMGZyYW1lYm9yZGVyJTNEJTIybm8lMjIlMjBzcmMlM0QlMjJodHRwcyUzQSUyRiUyRnBsYXllci53YnVyLm9yZyUyRmhlcmVhbmRub3clMkYyMDIzJTJGMDMlMkYxNiUyRm92YXJpYW4tY2FuY2Vycy1mYWxsb3BpYW4tdHViZXMlMjIlM0UlM0MlMkZpZnJhbWUlM0U=Removing fallopian tubes can prevent ovarian cancers without causing menopause. But who's eligible? The American Cancer Society estimates that more than 19,000 women will be diagnosed with ovarian cancer this year. More than 13,000 of them will die from the disease, which is difficult to diagnose and to treat. That's why the Ovarian Cancer Research Alliance recommended earlier this year that women (particularly those done having children) consider adding surgery to remove their fallopian tubes to pelvic surgeries like hysterectomies or tubal ligations since most ovarian cancers start in the tubes. Among those performing the surgery is Dr. Michael Worley,......

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More physicians are calling for fallopian tube removal to prevent ovarian cancer By Zeina Mohammed — Boston GlobeFeb. 23, 2023 Ovarian cancer has long been one of the deadliest cancers to strike women. No tests are available to detect it early, so most patients are diagnosed in later stages, when the cancer is more likely to have spread. Fewer than half of women survive 5 years past their diagnosis, and 80 percent have no known risk factors. Now, a growing chorus of physicians is recommending a procedure that can significantly reduce the chances of developing ovarian cancer. The procedure is......

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In some cases, those who are done with childbearing may be advised to have tubes removed if they are having another gynecological surgery anyway By Teddy Amenabar, Amy Goldstein and Lindsey Bever To prevent more cases of ovarian cancer, a major research and advocacy group is suggesting an aggressive prevention strategy: remove a woman’s fallopian tubes if she is undergoing pelvic surgery for another reason. The practice would apply to women, trans men or nonbinary people at average risk who don’t plan to have any or additional children. The fallopian tubes are hollow structures that allow eggs to travel from......

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Published on August 8, 2022 at Forbes.com Written by Russell Flannery   MIT Professor Tyler Jacks has made a mark in cancer work not only by his research but his ability to bring different organizations together. Through his leadership, Break Through Cancer has spurred a first-of-its-kind collaboration of five of the top cancer research centers in the world: Dana-Farber Cancer Institute, The Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, MIT’s Koch Institute for Integrative Cancer Research, The University of Texas MD Anderson Cancer Center, and Memorial Sloan Kettering Cancer Center. The effort, funded with $250 million of help from......

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