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Careers

JOIN OUR TEAM

Break Through Cancer is a 501(c)3. We are a growing team based in Cambridge, MA. We offer full benefits, competitive salaries, and are committed to equal opportunities in employments. Learn more about our open positions below.
To apply for any of these positions please submit a cover letter and CV or resume to careers@breakthroughcancer.org

Data Science Engineer

 Join us at Break Through Cancer for a once in a lifetime opportunity with the potential to impact millions of lives. A distinctly new type of foundation, Break Through Cancer empowers outstanding researchers and physicians to intercept, as well as find cures, for the deadliest cancers by stimulating radical collaboration. It represents a first-in-kind partnership between five of the top cancer research centers in the world: Dana-Farber Cancer Institute, Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, MIT’s Koch Institute for Integrative Cancer Research, The University of Texas MD Anderson Cancer Center, and Memorial Sloan Kettering Cancer Center. 

Break Through Cancer is focused on diseases with poor prognoses for which progress has been very slow: initially, glioblastoma, AML, ovarian, and pancreas cancers. We are looking beyond conventional therapies, utilizing new strategies, structures, and thinking from across disciplines, with the goal of enabling discoveries at an unprecedented pace and supporting radical collaboration between academic institutions as well as industry partners. 

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 Position Summary 

Alongside some of the finest minds in cancer research, you will tackle some of the hardest open problems in areas of greatest unmet need and apply the results directly to patient treatment across the nation. Part of what makes Break Through Cancer compelling is our founding principle that computational methods and data are an integral part of the entire research, development, and treatment process—not merely a quantitative afterthought. This ethos is codified into the design of our first-of-kind Data Science Hub, which aims to rapidly unify the most advanced patient and molecular data with analysis methods and visual tools to analyze and explore them, making all of it accessible in as timely, frictionless, and simple manner as possible––regardless of one’s level of technical sophistication. As an enabler of biological discovery and facilitator of patient treatment, the Data Science Hub will be a vital strategic asset in our portfolio and bedrock element of all disease research teams and clinical efforts. 

In this role you will provide data engineering, bioinformatics, and software development expertise to interdisciplinary projects ranging from basic research & discovery to clinical sample processing & analysis and machine learning models. Motivated by the chance to help decipher fundamental biological processes that directly impact patient outcomes, the ideal candidate will exude a deep passion for science and through this 

  • co-develop or maintain pipelines, software, databases and UIs 
  • embrace governance of & access to internal & external data 
  • continuously improve scalability, software & data quality, and SOPs 
  • harden, benchmark, and deploy novel bio-informatic methods 
  • iterate with stakeholders on requirements gathering 
  • help identify & fill gaps in data, software tools and documentation 
  • review and/or contribute to papers and presentations 

Key Experience and Skills 

  • B.S. in Bioinformatics, CS, Math, Biology (M.S. or Ph.D. a strong plus) 
  • 2-5 years’ experience doing academic/clinical/biotech bioinformatics 
  • Coding skill in Python, R, SQL/NoSQL, HTML, JavaScript, UNIX shell 
  • Extracting insight from rapidly evolving and/or unstructured data 
  • APIs and tools to warehouse, process & compute upon data 
  • Root cause of failure analysis on complex systems 
  • Visual portals/dashboards with Jupyter, PANDAS, Streamlit, Shiny 
  • High-throughput computation on the cloud (GCP, AWS, Azure) 
  • Strong attention to detail, oral & written communication skills 
  • Working from incomplete information, without micromanagement 
  • Systematically prioritize deliverables across multiple projects 
  • Positive attitude, strong drive & resilience in face of challenges 
  • Integrate external software tools, data repositories or research into concrete deliverables aligned with organizational goals 

Bonus Experience and Skills 

  • NextFlow, CWL, WDL workflow orchestration languages 
  • Terra, Synapse, Code Ocean, Foundry data / analysis systems 
  • Storage, analysis & interpretation of: DNA+RNA sequence data (bulk, single cell), spatial profiling & pathology images, clinical data 
  • Multi-omic bioinformatics, data cleansing, integration & analysis 
  • Biomarker discovery, clinical trial sample processing and analysis 
  • Cloud and/or big data tools: e.g. Docker, Kubernetes, Spark, Kafka 
  • Oncology, immunology, immunotherapies for cancer 

Break Through Cancer is committed to providing equal opportunities in employment and prohibits discrimination and harassment of any kind. We treat our fellow Break Through Cancer colleagues and Break Through Cancer applicants fairly and respectfully. We seek to employ people with skill and integrity, and provide them with the means to develop professionally. We hire without regard to race, color, religion, creed, citizenship, national origin, age, sex, gender, pregnancy, gender identity/expression, sexual orientation, marital status, disability (including neurodiversity), genetic information, veteran status, and any other legally protected group, in accordance with applicable federal, state, or local law. 

To apply, please submit a cover letter and cv to: info@breakthroughcancer.org 

Senior Director of Strategic Alliances and Program Management

Break Through Cancer is a new type of foundation which empowers outstanding researchers and physicians to intercept, as well as find cures, for the deadliest cancers by stimulating radical collaboration. It represents a first-of-its-kind collaboration of five of the top cancer research centers in the world: Dana-Farber Cancer Institute, Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, MIT’s Koch Institute for Integrative Cancer Research, The University of Texas MD Anderson Cancer Center, and Memorial Sloan Kettering Cancer Center.

Break Through Cancer is focused on several of the world’s deadliest cancers: initially glioblastoma, AML, ovarian, and pancreas cancers. These are diseases with poor prognoses for which progress has been very slow. We are looking beyond conventional therapies, utilizing new strategies, structures, and thinking from across disciplines, with the goal of enabling discoveries at an unprecedented pace. A key part of our strategy is to create technology and systems that make sharing data in real time frictionless. We believe that sophisticated computational infrastructure and analysis platforms are critical to support radical collaboration between academic institutions and between academia and industry.

Break Through Cancer’s success will rely on mission-driven partners who share our sense of urgency to transform the cancer ecosystem to support the next generation of cancer treatment and prevention. Break Through Cancer has initiated discussions with pharma, biopharma, biotech, and high-tech companies to explore ways of working together as part of a shared community. This community will be centered around the Break Through Cancer Industry Partner Alliance, a membership model for pharma and biotech, which will be supported by a suite of multi-institutional sponsored research and clinical trial agreements designed to simplify interactions and foster scientific progress.

Break Through Cancer seeks an experienced, organized, passionate, and enthusiastic Senior Director of Strategic Alliances and Program Management to report to the Chief Science Officer. The Senior Director will be responsible for the Break Through Cancer Industry Partner Alliance (IPA), including the formation and stewardship of strategic partnerships that help to foster the work of Break Through Cancer teams, establishing and/or strengthening relationships with a diverse set of biotech and pharma partners, identifying opportunities for new alliances, and developing strategies to ensure partnerships are beneficial to all parties. The Senior Director will also be responsible for overseeing the Program and Project Management team, who work with clinicians, researchers, technologists, IRBs, and other collaborators at partner institutions to manage project timelines and deliverables, including understanding and navigating interdependencies.

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Responsibilities include:

  • Working closely with the Chief Science Officer and members of Break Through Cancer-funded teams to understand the strategic needs of the different projects and identify partnerships that will support the research;
  • Serve as an alliance and programmatic point of contact, working closely with institutional team members and industry partners to advance, manage, monitor, and report out (to various audiences ranging from collaborators to boards) on joint goals, progress, issues, and overall health of the collaboration;
  • Oversee programmatic activities and manage escalations to ensure successful collaboration, initiation, and execution of projects between industry and institutional partners;
    Lead alliance and programmatic risk and issue management including proactively identifying potential challenges in collaborative research including management of human subjects and intellectual property obligations, contingencies, timelines, and resources. managing issues to resolution;
  • Ensure engagement of institutional and industry partners by fostering and maintaining collaborative working relationships;
    Manage collaboration governance and operating norms (including support of joint committees) with special attention to alignment of team member and to the foundation goals and operating principals prior to joint decisions;
    Work closely with Break Through Cancer-funded teams to gain internal championship for successful execution of existing project plans and expansion into new partnership plans;
  • Develop a network of strong advocates across partner institutions with a view of building a map of decision makers, influencers, and champions who can directly impact the successful implementation of the IPA;
    Provide operational oversight and metrics that focuses on the integrity, scalability, cost effectiveness, and overall process efficiency in the IPA;
  • Working closely with project teams at the Participating Institutions to align and provide oversight to the implementation and maintenance of shared project management plans and community for project teams;
    Working closely with Break Through Cancer Chief Financial Officer to prepare and monitor project budgets and expenditures;
    Proactively obtain collaborator feedback on the effectiveness of the collaboration. Help to identify, facilitate, and steward changes where necessary and appropriate to maintain a highly effective collaboration; and
  • Ensure that alliances and programs are managed consistently, drive implementation of alliance and program management best practices, standard tools and approaches.Qualifications
    7+ years of experience in alliance management, business development, life sciences, or related field;
  • Experience building and managing successful relationships with institutions, scientists, clinicians, Pharma/Biotech;
    Deep understanding of cancer research and clinical trials;
  • Experience working with and managing cross-functional teams, including joint leadership or governance committees, to accomplish shared goals;
  • Excellent business acumen with demonstrated ability to develop solutions that support product, team, corporate, and alliance objectives;
  • Strong facilitation, problem-solving, and issue resolution skills;
    Adaptive leadership style with ability to influence teams without formal authority; demonstrated ability to collaborate across multiple stakeholder groups to advance priorities;
  • Excellent interpersonal /relationship management skills and proven ability to facilitate internal alignment;
  • Ability to effectively and diplomatically negotiate and resolve conflicts; and
  • Excellent verbal and written communication skills; ability to connect with a variety of stakeholders.

To apply for this position, please submit a cover letter and cv to: info@breakthroughcancer.org

Break Through Cancer is committed to providing equal opportunities in employment and prohibits discrimination and harassment of any kind. We treat our fellow Break Through Cancer colleagues and Break Through Cancer applicants fairly and respectfully. We seek to employ people with skill and integrity, and provide them with the means to develop professionally. We hire without regard to race, color, religion, creed, citizenship, national origin, age, sex, gender, pregnancy, gender identity/expression, sexual orientation, marital status, disability (including neurodiversity), genetic information, veteran status, and any other legally protected group, in accordance with applicable federal, state, or local law.

Managing Director of DEVELOPMENT

Break Through Cancer is a new foundation that empowers outstanding researchers and physicians to intercept, as well as find cures, for the deadliest cancers by stimulating radical collaboration. It represents a first-of-its-kind collaboration of five of the top cancer research centers in the world: Dana-Farber Cancer Institute, Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, MIT’s Koch Institute for Integrative Cancer Research, The University of Texas MD Anderson Cancer Center, and Memorial Sloan Kettering Cancer Center.
Break Through Cancer is focused on several of the world’s deadliest cancers: initially glioblastoma, AML, ovarian, and pancreas cancers. These are diseases with poor prognoses for which progress has been very slow. We are looking beyond conventional therapies, utilizing new strategies, structures, and thinking from across disciplines, with the goal of enabling discoveries at an unprecedented pace. A key part of our strategy is to create technology and systems that make sharing data in real time frictionless. We believe that sophisticated computational infrastructure and analysis platforms are critical to support radical collaboration between academic institutions and between academia and industry.

Break Through Cancer seeks a driven, experienced fundraiser to help raise at least $250M as part of the Foundation’s inaugural matching gift. The MDD will engage prospective individual donors nationally and internationally and maintain a portfolio of prospects with responsibility for donor identification, research, cultivation, solicitation, and stewardship, as well as serving as a strategic partner to Break Through Cancer’s President, Chief Operating Officer/Chief Philanthropy Officer, and other key foundation leaders. The MDD will arrange both on and off-site meetings, cultivation, and stewardship visits/events with members of funded teams, BTC leadership, prospects, and donors. Working with the Chief Philanthropy Officer, the MDD will coordinate with the Break Through Cancer Philanthropy Committee (made up of members from each of the five participating institutions). The MDD will also be responsible for annual donor reporting and maintaining a prospect/donor database.

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Qualifications

  • Minimum of ten years of fundraising experience (preferably with some principal gifts) in a complex academic and/or healthcare setting required;
  • Experience with cancer and/or research fundraising;
  • Ability to communicate the excitement and promise of Break Through Cancer’s funded projects, and help shape those priorities to inspire support from donors;
  • Ability to manage complex issues creatively and sensitively;
  • Excellent oral, written, and interpersonal communication skills; and
  • Bachelor’s degree required; advanced degree preferred.

Break Through Cancer is committed to providing equal opportunities in employment and prohibits discrimination and harassment of any kind. We treat our colleagues and applicants fairly and respectfully. We seek to employ people with skill and integrity, and provide them with the means to develop professionally. We hire without regard to race, color, religion, creed, citizenship, national origin, age, sex, gender, pregnancy, gender identity/expression, sexual orientation, marital status, disability (including neurodiversity), genetic information, veteran status, and any other legally protected group, in accordance with applicable federal, state, or local law.

PROJECT MANAGER

Break Through Cancer seeks an organized, passionate, and enthusiastic Project Manager to report to the Program Management Team Lead under the Chief Science Officer. The primary responsibilities of these roles will be to work closely within one of our specific disease areas to manage timelines, deliverables, and expenditures for specific project(s) and to work closely to support Break Through Cancer-funded scientists to proactively identify and overcome key executional barriers.

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Break Through Cancer is a new foundation which empowers outstanding researchers and physicians to intercept, as well as find cures, for the deadliest cancers by stimulating radical collaboration. It represents a first-of-its-kind collaboration of five of the top cancer research centers in the world: Dana-Farber Cancer Institute, Johns Hopkins Sidney Kimmel Comprehensive Cancer Center, MIT’s Koch Institute for Integrative Cancer Research, The University of Texas MD Anderson Cancer Center, and Memorial Sloan Kettering Cancer Center.

Break Through Cancer is focused on several of the world’s deadliest cancers: initially glioblastoma, AML, ovarian, and pancreas cancers. These are diseases with poor prognosis for which progress has been very slow. We are looking beyond conventional therapies, utilizing new strategies, structures, and thinking from across disciplines, with the goal of enabling discoveries at an unprecedented pace. A key part of our strategy is to create technology and systems that make sharing data in real time frictionless. We believe that sophisticated computational infrastructure and analysis platforms are critical to support radical collaboration between academic institutions and between academia and industry.

Break Through Cancer seeks an organized, passionate, and enthusiastic Project Manager to  report to the Program Management Team Lead under the Chief Science Officer. The primary  responsibilities of these roles will be to work closely within one of our specific disease areas to  manage timelines, deliverables, and expenditures for specific project(s) and to work closely to  support Break Through Cancer-funded scientists to proactively identify and overcome key  executional barriers. 

Responsibilities  

  • Managing specific project(s) within the Break Through Cancer portfolio of projects; Working closely with embedded project managers and scientists at world class cancer  research centers across the country to align goals and meet timelines and deliverables; 
  • Schedule, manage and provide support for team meetings, project review presentations  and written project reports; 
  • Manage and track project progress and communicate with stakeholders, and as needed,  develop team and project metrics for monitoring success;
  • Working to revise and manage IRB protocols and inter-institutional legal agreements  related to project(s); 
  • Preparing and monitoring project budgets and expenditures; 
  • Work closely with computational experts to gain an understanding of data processing  methods and tools 
  • Working closely with data manager(s) to oversee the appropriate flow of data into a  shared cloud environment, as well as maintaining access control  lists; 
  • Organize training sessions and engagement activities including retreats, in-person team  meetings, and hackathons; 
  • Preparing notes and minutes for key scientific meetings and well as strategic  programmatic memoranda; and 
  • Other duties as assigned. 

Qualifications 

  • Advanced degree in Cancer Biology or equivalent experience; 
  • Expertise managing projects related to human subjects and large-scale datasets preferred—ideally in both academic and industry environments ; 
  • Expertise with project management and communication tools 
  • Familiarity with programming and command-line tools required; 
  • Familiarity with financial reporting; 
  • Growth mindset with the desire to work in a collaborative environment to promote and  drive superior team performance; 
  • Demonstrated ability to succeed in a fast-paced, dynamic, and high growth  environment; 
  • Excellent external and internal communication, organizational; and 
  • Solutions-oriented problem solver. 

Break Through Cancer is committed to providing equal opportunities in employment and  prohibits discrimination and harassment of any kind. We treat our fellow Break Through Cancer  colleagues and Break Through Cancer applicants fairly and respectfully. We seek to employ  people with skill and integrity, and provide them with the means to develop professionally. We  hire without regard to race, color, religion, creed, citizenship, national origin, age, sex, gender,  pregnancy, gender identity/expression, sexual orientation, marital status, disability (including  neurodiversity), genetic information, veteran status, and any other legally protected group, in  accordance with applicable federal, state, or local law. 

To apply for the Project Manager role, please send a cover letter and CV to info@breakthroughcancer.org

Break Through Cancer is committed to providing equal opportunities in employment and prohibits discrimination and harassment of any kind. We treat our fellow Break Through Cancer colleagues and Break Through Cancer applicants fairly and respectfully. We seek to employ people with skill and integrity, and provide them with the means to develop professionally. We hire without regard to race, color, religion, creed, citizenship, national origin, age, sex, gender, pregnancy, gender identity/expression, sexual orientation, marital status, disability (including neurodiversity), genetic information, veteran status, and any other legally protected group, in accordance with applicable federal, state, or local law.

To apply please submit a cover letter and CV or resume to careers@breakthroughcancer.org

MAKE A DIFFERENCE

Break Through Cancer was created in February 2021 with an extraordinary matching gift of $250,000,000. Every gift to the Foundation supports groundbreaking cancer research and helps us to meet our matching commitment.

For questions about giving please email Lisa Schwarz, Chief Philanthropy Officer at LMS@BreakThroughCancer.org

Break Through Cancer
PO Box 390450
770 Massachusetts Avenue
Cambridge, MA 02139

Info@breakthroughcancer.org
1-800-757-9881