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Careers

Paving the future of cancer research requires creative, driven individuals who think differently about solutions to fundamental challenges blocking progress for cancer patients. Break Through Cancer is a new cancer research foundation that is bringing together research teams across five leading cancer institutions to produce general frameworks to make inter-institutional cancer research frictionless and impactful.

Beginning in four intractable cancers: glioblastoma, AML, ovarian, and pancreas cancers, we aim to align the worlds of preclinical and clinical research closer than ever before, learn directly from patient experiences, and invest in software and technologies that will enhance user experiences. Break Through Cancer-funded project teams will create new approaches to test emerging hypotheses in patients as rapidly as possible and intervene for high risk patients as early as possible, including through vaccination.

Open Positions

Be a part of the Break Through Cancer team. To apply, please submit a cover letter and resume or CV to careers@breakthroughcancer.org

Program Management Lead

Paving the future of cancer research requires creative and driven individuals who think differently about solutions to fundamental challenges blocking progress for cancer patients. Break Through Cancer is a new type of research foundation whose mission is to promote and support inter-institutional, collaborative cancer research in order to better understand and treat the most intractable forms of human cancer. By aligning research teams across five leading cancer institutions, Break Through Cancer seeks to create frameworks to make inter-institutional cancer research frictionless and impactful.

Beginning with four intractable cancers: glioblastoma, AML, ovarian and pancreas cancers, Break Through Cancer hopes to bring together the worlds of preclinical and clinical research closer than ever before, learn directly from patient experiences, and invest in software and technologies that will enhance user experiences. Break Through Cancer-funded project teams will create new approaches to test emerging hypotheses in patients as rapidly as possible and intervene for high risk patients as early as possible, including through vaccination.

Making project teams across five institutions function as if they were all working within the same laboratory requires world-class program management, including strengthening relationships and alliances, overseeing compliance/IRB and intellectual property obligations, and managing projects and deliverables to succeed on appropriate timelines. Projects will include new clinical trial formats, new laboratory experiments, and complex relationships with academic, hospital, and industry partners. Excellent program management to empower project teams and deliver impact is mission-critical to Break Through Cancer’s success.

Break Through Cancer seeks an organized, passionate, and enthusiastic Program Manager to report to the Chief Science Officer. The primary responsibilities of this role will be to work closely with project teams, IRBs, and other collaborators at the partner institutions to manage project timelines and deliverables, including understanding and navigating interdependencies. As we develop industry partnership models, the successful candidate will play a key role in overseeing these relationships and activities.

Responsibilities include but are not limited to:

  • Managing a multimillion dollar project portfolio of Break Through Cancer funded projects;
  • Working closely with project teams at University of Texas MD Anderson Cancer Center, Dana-Farber Cancer Institute, Memorial Sloan Kettering Cancer Center, MIT’s Koch Institute for Integrative Cancer Research, and Johns Hopkins Kimmel Cancer Center to implement and maintain a shared project management plan and community for project teams;
  • Manage project review presentations and written project reports;
  • Managing and developing direct project managers as required by Break Through Cancer and teams, likely beginning in a year or two;
  • Identifying and overcoming potential challenges in collaborative research including management of human subjects and intellectual property obligations, contingencies, risks, and timelines;
  • Working closely with Break Through Cancer Chief Financial Officer to prepare and monitor project budgets and expenditures;
  • Working closely with Break Through Cancer Chief Science Officer to lead joint lab meetings consisting of project team members;
  • Working closely with Break Through Cancer Data Manager to oversee the appropriate flow of data to support projects;
  • Leading alliance management activities for Industry partnerships;
  • Preparing notes and minutes for key scientific meetings and well as strategic programmatic memoranda;
  • Consistently performing needs assessments and making strategic recommendations to CSO;
  • Working closely with Break Through Cancer CSO and other members of the Executive Leadership Team to provide updates/presentations to theScientific Advisory Board and Board of Directors; and
  • Other duties as assigned.

The successful candidate will gain exposure to working with leading cancer researchers across the United States, and, as such, affords great professional development potential.

Skills/Requirements:

  • PhD in Cancer Biology or related field
  • MBA and/or PMP certification preferred
  • 3-5 years of related program management experience including working with diverse stakeholders in a complex, matrixed environment;
  • Expertise with clinical trial design, work with IRBs and industry partnerships
  • Expertise with medical records, genomic, and clinical data
  • Extensive experience managing human subjects and identifiability challenges
  • Growth mindset with the desire to work in a collaborative environment to promote and drive superior team performance
  • Demonstrated ability to succeed in a fast-paced, dynamic, and high growth technology environment
  • Excellent customer-facing and internal communication, organizational, and verbal/written communication skills
  • Solutions-oriented problem solver

Break Through Cancer is committed to providing equal opportunities in employment and prohibits discrimination and harassment of any kind.  We treat our fellow Break Through Cancer colleagues and Break Through Cancer applicants fairly and respectfully. We seek to employ people with skill and integrity, and provide them with the means to develop professionally. We hire without regard to race, color, religion, creed, citizenship, national origin, age, sex, gender, pregnancy, gender identity/expression, sexual orientation, marital status, disability (including neurodiversity), genetic information, veteran status, and any other legally protected group, in accordance with applicable federal, state, or local law.

To apply, please submit a cover letter and resume or CV to careers@breakthroughcancer.org

Data Management Lead

Paving the future of cancer research requires creative and driven individuals who think differently about solutions to fundamental challenges blocking progress for cancer patients. Break Through Cancer is a new type of research foundation whose mission is to promote and support inter-institutional, collaborative cancer research in order to better understand and treat the most intractable forms of human cancer. By aligning research teams across five leading cancer institutions, Break Through Cancer seeks to create frameworks to make inter-institutional cancer research frictionless and impactful.

Beginning with four intractable cancers: glioblastoma, AML, ovarian and pancreas cancers, Break Through Cancer hopes to bring together the worlds of preclinical and clinical research closer than ever before, learn directly from patient experiences, and invest in software and technologies that will enhance user experiences. Break Through Cancer-funded project teams will create new approaches to test emerging hypotheses in patients as rapidly as possible and intervene for high risk patients as early as possible, including through vaccination.

Helping project teams across five institutions to function as if they were all working within the same laboratory requires world-class solutions for data management. Data sources, including medical records, abstracted clinical data, medical imaging data, molecular profiling/genomics data, single cell profiling data and other forms of laboratory data will be derived from and shared by multiple institutions. Creating and managing a data framework to empower project teams is mission critical for Break Through Cancer’s success.


Break Through Cancer seeks an organized, passionate, and enthusiastic data manager to make this work possible. Reporting to the Chief Science Officer, the primary responsibilities of this role will be to liaise closely with data scientists, software engineers, and information security professionals at each of the five institutions to develop and maintain Break Through Cancer data infrastructure to make data sets, both funded by Break Through Cancer and generated through other funding sources, findable, accessible, interoperable, and reusable to achieve the goals of the project teams.

Responsibilities include but are not limited to:

  • Working closely with data scientists at University of Texas MD Anderson Cancer Center, Dana-Farber Cancer Institute, Memorial Sloan Kettering Cancer Center, MIT’s Koch Institute for Integrative Cancer Research, and Johns Hopkins Kimmel Cancer Center to implement and maintain a shared cloud environment with appropriate data security and access controls;
  • Working closely with project teams to bring existing datasets into the shared environment, through management of human subjects and intellectual property obligations, meta-data standardization, and overcoming data formatting challenges;
  • Working closely with Break Through Cancer Program Manager to oversee the appropriate flow of data to support projects;
  • Working closely with software engineers and computational biologists at the Institutions and on Break Through Cancer-funded teams to evaluate existing tools and pipelines, benchmark outputs, and recommend solutions;
  • Developing data documentation and curation to support provenance tracking, attribution, and usage restrictions;
  • Interacting with other cancer foundations to evaluate data solutions and making strategic recommendations about areas of collaboration or intersection;
  • Working closely with operations and alliance project management to support the timely execution of data-related tasks, including timed data release cycles;
  • Organizing training sessions and outreach activities to enable clinicians, basic researchers, and others utilize best of class portals and resources;
  • Playing a major role in all Break Through Cancer-funded projects that include software and data components, bringing scientific and computational ideas and strategies to bear on project directions;
  • Consistently performing needs assessments and making strategic recommendations to the Chief Scientific Officer (CSO);
  • Providing technical assistance and training to junior team members/collaborators in the use of developed information systems;
  • Working closely with Break Through Cancer CSO and other members of the Executive Leadership Team to provide updates and presentations to the Scientific Advisory Board and Board of Directors;
  • Other duties and responsibilities as assigned.

The successful candidate will gain exposure to working with leading cancer researchers across the United States, and as such, affords great professional development potential.

Skills/Requirements:

  • MS/PhD in Computer Science, bioinformatics or related field
  • 3-5 years of work-related computational biology experience including working with genomic data, clinical data, medical records
  • Extensive experience managing human subjects and identifiability challenges
  • Proficiency in multiple coding languages, including R, Python or others
  • Proficiency in relational database design and maintenance
  • Proficiency in managing cloud computing environments
  • Ability to work in a collaborative environment to promote and drive superior team performance
  • Demonstrated ability to succeed in a fast-paced, dynamic, and high growth technology environment
    Excellent customer-facing and internal communication skills, organizational skills, verbal/written communications
  • Solutions-oriented problem solver

Break Through Cancer is committed to providing equal opportunities in employment and prohibits discrimination and harassment of any kind. We treat our fellow Break Through Cancer colleagues and Break Through Cancer applicants fairly and respectfully. We seek to employ people with skill and integrity, and provide them with the means to develop professionally. We hire without regard to race, color, religion, creed, citizenship, national origin, age, sex, gender, pregnancy, gender identity/expression, sexual orientation, marital status, disability (including neurodiversity), genetic information, veteran status, and any other legally protected group, in accordance with applicable federal, state, or local law.
To apply, please submit a cover letter and resume or CV to careers@breakthroughcancer.org

Break Through Cancer is committed to providing equal opportunities in employment and prohibits discrimination and harassment of any kind. We treat our fellow Break Through Cancer colleagues and Break Through Cancer applicants fairly and respectfully. We seek to employ people with skill and integrity, and provide them with the means to develop professionally. We hire without regard to race, color, religion, creed, citizenship, national origin, age, sex, gender, pregnancy, gender identity/expression, sexual orientation, marital status, disability (including neurodiversity), genetic information, veteran status, and any other legally protected group, in accordance with applicable federal, state, or local law.

Make a difference

Break Through Cancer was created in February 2021 with an extraordinary matching gift of $250,000,000. Every gift to the Foundation supports groundbreaking cancer research and helps us to meet our matching commitment.

For questions about giving please email LMS@BreakThroughCancer.org