Break Through Cancer
Radical Collaboration
Data Show MRD in Nearly Half of Ovarian Cancer Population in Remission August 04, 2025 Further studying the biology of minimal residual disease may uncover ovarian cancer vulnerabilities and inform more effective therapies. Author: Russ Conroy Fact checked by: Roman Fabbricatore Read More at CancerNetwork...
To prevent ovarian cancers, fallopian tube removal is on the rise There’s long been confusion between ‘tube-tying’ and salpingectomy. Now, oncologists are trying to dispel it June 16, 2025 To Rebecca Stone, the single most important fact about ovarian cancer is that it’s usually a misnomer. The most common kind — responsible for 70% of cases and 90% of deaths — often has its silent beginnings not in the ovary, but in the fallopian tube. This isn’t just an interesting factoid; as a gynecologic oncologist at Johns Hopkins, Stone sees it as a reason to evangelize. There’s no way to......
I had one simple surgery to lower my risk of the deadliest cancer for women. Here’s why you probably don’t know about it—but should June 16, 2025 I woke up from surgery groggy, with three minuscule incisions in my abdomen and huge peace of mind. I’d just had my fallopian tubes laparoscopically removed, as it’s the best—and possibly only—defense against ovarian cancer, which, though rare, is the most lethal gynecological cancer there is. Read More at Fortune Well...
Accelerating Discovery: Break Through Cancer’s 2nd Annual Hackathon This June, Break Through Cancer hosted its 2nd Annual Hackathon at the Broad Institute, bringing together 67 participants across seven TeamLabs for two days of intense, cross-disciplinary problem solving. Researchers, clinicians, data coordinators, and Break Through Cancer staff worked side by side to tackle some of the most pressing analytical challenges across glioblastoma, ovarian, and pancreatic cancer. Radical Collaboration in Action Hackathons are designed to spark innovation by bringing together people who don’t normally sit in the same room. For Break Through Cancer, they are a natural extension of our TeamLab......
New collaborative effort aims to cure ALK-positive lung cancer December 6, 2024 Lung cancer is the leading cause of cancer death worldwide, with various subtypes affecting millions of people each year. Among these, ALK-positive lung cancer frequently strikes younger people who have never smoked, including those aged between 20 and 50. Upon diagnosis, 80% of individuals already have stage 4 metastatic cancer, spread beyond the lungs to other parts of the body. Despite initially effective ALK inhibitor treatments, the cancer recurs in most patients, and there are about 70,000 people living with ALK+ lung cancer in the United States. Read......
Break Through Cancer launches the PoweRD 2 Cure ALK+ Lung Cancer TeamLab December 6, 2024 Break Through Cancer has launched the PoweRD 2 Cure ALK+ Lung Cancer TeamLab, a collaboration among nine leading cancer research institutions, including Break Through Cancer’s five partner institutions: Dana-Farber Cancer Institute, Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins, Memorial Sloan Kettering Cancer Center, MIT’s Koch Institute for Integrative Cancer Research, and the University of Texas MD Anderson Cancer Center, as well as newly engaged collaborators from Mass General Brigham, Boston Children’s Hospital, the University of Colorado Cancer Center and Vanderbilt University Medical Center. Read......
Radical Collaboration: Reimagining Cancer Team Science By: Jesse Boehm and Tyler Jacks Here, we define a future of cancer team science adopting “radical collaboration”—in which six “Hallmarks of Cancer Collaboration” are utilized to propel cancer teams to reach new levels of productivity and impact in the modern era. This commentary establishes a playbook for cancer team science that can be readily adopted by others. Read More at Cancer Discovery...
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More physicians are calling for fallopian tube removal to prevent ovarian cancer By Zeina Mohammed — Boston GlobeFeb. 23, 2023 Ovarian cancer has long been one of the deadliest cancers to strike women. No tests are available to detect it early, so most patients are diagnosed in later stages, when the cancer is more likely to have spread. Fewer than half of women survive 5 years past their diagnosis, and 80 percent have no known risk factors. Now, a growing chorus of physicians is recommending a procedure that can significantly reduce the chances of developing ovarian cancer. The procedure is......
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