The Prognostic Value of Residual Disease in Ovarian Cancer
Authors: Sabrina Serani & Amir Jazaeri, MD
Fact checked by: Jason M. Broderick
August 22, 2025
Key Takeaways
- SLL and ctDNA are effective in detecting MRD in ovarian cancer, surpassing conventional methods like CA 125 and CT scans.
- SLL provides access to MRD tissue, offering insights into chemoresistance and potential therapeutic targets.
- CtDNA is a promising early surrogate endpoint in clinical trials, allowing earlier assessment of treatment efficacy.
- Identifying high-risk patients through these methods enables earlier intervention with innovative and investigational therapies.
UPDATES AND NEWS
We can prevent ovarian cancer. Women deserve the option. | USA Today
Fallopian tube removal may lower ovarian cancer risk | Good Morning America
The Lustgarten Foundation and Break Through Cancer Announce New Clinical Trial Evaluating KRAS-targeted Immunotherapy Strategy for Pancreatic Cancer
Most ‘Ovarian Cancer’ Isn’t. And That Fact Can Save Lives | New York Times
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