Break Through Cancer
Radical Collaboration
Why some family offices are becoming cancer research's new bankrollers March 13, 2026 | Marcus Baram Family offices are stepping in to fill a widening gap in cancer research funding, deploying billions of dollars of patient capital at a moment when federal cuts threaten to stall laboratories and AI breakthroughs promise to accelerate drug development. Read More at Crain Currency....
Break Through Cancer’s Tyler Jacks: “We’ve created a new operating model for collaborative cancer research. March 13, 2026 | Vol.52 No.10 Five years ago, Tyler Jacks took on a new challenge, becoming president of Break Through Cancer, a foundation that has pledged to spend at least $500 million to support research projects across top tier cancer centers. From the start, the foundation’s objective included fostering a change in culture in America’s top labs, ushering in what Jacks calls “radical collaboration” (The Cancer Letter, Feb. 25, 2021). Read More at The Cancer Letter. Watch Tyler's Conversation with Paul here:...
One Surgery Could Prevent Most Ovarian Cancers, Surgeons Say November 20, 2025 Known as “the silent killer” due to its lack of symptoms and reliable screening tests, ovarian cancer remains one of the deadliest gynecologic cancers, claiming more than 12,000 lives annually. At a recent meeting, experts said that performing a single preventive procedure within general surgery could stop many ovarian cancers from ever developing. Read More at The ASCO Post....
Jesse Boehm at the Future of Health Summit 2025: Conquering Cancer Panel We are pleased to share that our Chief Scientific Officer, Jesse Boehm, participated as a speaker at the 2025 Future of Health Summit, hosted by the Milken Institute in Washington, DC. The Summit brought together more than 200 experts and 1,400 participants to discuss biomedical innovation, equitable access, chronic disease prevention, and the future of global health. As part of the program, Jesse joined the panel “Conquering Cancer: Innovations, Closing Gaps and Improving Outcomes,” contributing perspectives on the power of radical collaboration and team-science models to accelerate progress......
Canadian scientists join international osteosarcoma team to solve aggressive cancer that targets children and young adults November 14, 2025 More than 45 years after Terry Fox ran his Marathon of Hope, a new generation of scientists—backed by a coalition of donors and home-grown Canadian ingenuity—unites to defeat osteosarcoma, the cancer that took Terry's life. Read More at Globe and Mail....
One Surgery Could Prevent Most Ovarian Cancers, Surgeons Say November 17, 2025 Expanding access to fallopian tube removal during planned abdominal surgeries in post-reproductive women could save thousands of lives every year. Read More at American College of Surgeons...
Real-Time Biopsies Reveal Hidden Insights into Glioblastoma Therapy Response October 08, 2025 In a groundbreaking advancement for glioblastoma research, scientists from Break Through Cancer’s Accelerating Glioblastoma Therapies Through Serial Biopsies TeamLab have demonstrated that the oncolytic virus therapy, CAN-3110, sparks a profound and previously undetectable immune response deep within recurrent glioblastoma tumors. Read More at Bioengineer.org...
Experimental Glioblastoma Trial Findings Could Lead to Change in Patient Monitoring and Therapy October 08, 2025 Researchers headed by teams at Mass General Brigham Cancer Institute and Harvard Medical School have acquired serial biopsies from two recurrent glioblastoma (rGBM) patients who were involved in an immunotherapy clinical trial, allowing the scientists to safely monitor brain tumor progression and the patients’ responses to treatment. The researchers say their approach captured details that are indiscernible by even the most advanced of imaging methods. Read More at Genetic Engineering and Biotechnology News...
Serial Biopsies Reveal Immune Activation During Treatment for Recurrent Glioblastoma October 08, 2025 by Mark Chiang A recent multi-institutional study has demonstrated that repeated sampling of brain tumor tissue can reveal immune system activation in response to cancer treatment for patients with recurrent glioblastoma (GBM). The research, conducted by the Accelerating GBM Therapies Through Serial Biopsies TeamLab and led by investigators from the Mass General Brigham Cancer Institute, highlights the potential of serial biopsies to detect treatment responses that may not be visible through traditional imaging techniques. Read More at Gene Online...
Break Through Cancer launches a $15M multi-institute pediatric osteosarcoma research initiative September 26, 2025 Vol.51 No.35 Break Through Cancer has launched the Defying Osteosarcoma TeamLab, an initiative that brings together more than 20 researchers from eight institutions in a coordinated, multi-year effort focused on improving pediatric osteosarcoma care. Read More at The Cancer Letter...
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