Break Through Cancer
Radical Collaboration
We can prevent ovarian cancer. Women deserve the option. | Opinion August 13, 2026 | USA Today Dr. Joseph Sakran and Dr. Rebecca Stone Cancer prevention opportunities are rare. When one presents itself safely during an operation a patient is already having, we have a responsibility to consider it. Read the full story on USA Today...
Fallopian tube removal may lower ovarian cancer risk August 10, 2026 | Good Morning America ABC News' Rhiannon Ally and chief medical correspondent Dr. Tara Narula report on a procedure that may reduce ovarian cancer risk by up to 80%. Watch the feature here...
Most ‘Ovarian Cancer’ Isn’t. And That Fact Can Save Lives. The vast majority of cases begin in the fallopian tubes — and removing them can reduce the risk by nearly 80 percent. July 28, 2026 | Gina Kolata Kira Wynn will do almost anything to avoid ovarian cancer, which killed her mother. “My mom thought she’d pulled a muscle in her side,” Ms. Wynn said. Her mother’s doctor, she added, “told her to do physical therapy.” As is often the case with ovarian cancer, Ms. Wynn’s mother’s disease was already at an advanced stage when she was diagnosed. She......
Break Through Cancer and the Lustgarten Foundation Launch New Pancreatic Cancer Initiative July 02, 2026 | The ASCO Post Staff At a pivotal moment for pancreatic cancer, Break Through Cancer and the Lustgarten Foundation, with support from the Cinelli Family Foundation, has announced a $16 million investment in the Conquering KRAS for Patients with Pancreatic Cancer TeamLab. Spanning six world-class cancer research institutions, this initiative aims to improve outcomes for one of the deadliest cancers by focusing on KRAS, a gene that is mutated in more than 90% of pancreatic cancer cases. Read More The ASCO Post....
How scientists found a weakness in one of the deadliest 'undruggable' cancers May 24, 2026 | Calrolyn Johnson “This is the news we've been waiting for. This is the breakthrough — it's been a long time coming,” said Break Through Cancer President Tyler Jacks, PhD, in a recent Washington Post feature examining the decades-long scientific effort that led to KRAS-targeted therapies for pancreatic cancer. In this new article for The Washington Post, Carolyn Johnson traces the scientific journey behind daraxonrasib, from the early discovery of KRAS as a cancer driver to the clinical results that are reshaping expectations for one......
Radical Collaboration: A Cancer Funder Seeks to Solve the Problem of Siloed Research April 20, 2026 | Paul Karon Back in 2021, I wrote about Break Through Cancer, then a newly launched organization focused on addressing a literally deadly problem: overly siloed, disconnected research on the second-leading cause of death in the U.S. and worldwide. Beyond funding research, Break Through Cancer’s leaders seek to create a more effective way to build and operate research teams that span multiple specialties, labs and institutions — the better to untangle cancer’s toughest challenges and develop better ways to diagnose and treat patients. While collaboration between......
Why some family offices are becoming cancer research's new bankrollers March 13, 2026 | Marcus Baram Family offices are stepping in to fill a widening gap in cancer research funding, deploying billions of dollars of patient capital at a moment when federal cuts threaten to stall laboratories and AI breakthroughs promise to accelerate drug development. Read More at Crain Currency....
Break Through Cancer’s Tyler Jacks: “We’ve created a new operating model for collaborative cancer research. March 13, 2026 | Vol.52 No.10 Five years ago, Tyler Jacks took on a new challenge, becoming president of Break Through Cancer, a foundation that has pledged to spend at least $500 million to support research projects across top tier cancer centers. From the start, the foundation’s objective included fostering a change in culture in America’s top labs, ushering in what Jacks calls “radical collaboration” (The Cancer Letter, Feb. 25, 2021). Read More at The Cancer Letter. Watch Tyler's Conversation with Paul here:...
One Surgery Could Prevent Most Ovarian Cancers, Surgeons Say November 20, 2025 Known as “the silent killer” due to its lack of symptoms and reliable screening tests, ovarian cancer remains one of the deadliest gynecologic cancers, claiming more than 12,000 lives annually. At a recent meeting, experts said that performing a single preventive procedure within general surgery could stop many ovarian cancers from ever developing. Read More at The ASCO Post....
Jesse Boehm at the Future of Health Summit 2025: Conquering Cancer Panel We are pleased to share that our Chief Scientific Officer, Jesse Boehm, participated as a speaker at the 2025 Future of Health Summit, hosted by the Milken Institute in Washington, DC. The Summit brought together more than 200 experts and 1,400 participants to discuss biomedical innovation, equitable access, chronic disease prevention, and the future of global health. As part of the program, Jesse joined the panel “Conquering Cancer: Innovations, Closing Gaps and Improving Outcomes,” contributing perspectives on the power of radical collaboration and team-science models to accelerate progress......
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